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All of the active B12 group hair reporting showed reduction in severity of symptoms ranging from 31% to 70%, while the placebo controls reported either no change or a worsening of symptoms. Wilcoxon-Rank of .002 for the end-points extensions of sneezing, nasal congestion and runny nose; and p = .005 for IgE reductions. funky In 1992, the above mentioned data from 1988 on were presented by Dr. O''Connor to the FDA. The FDA hair panel acknowledged the safety of the treatment. The panel seemed to be in agreement extensions that funky the statistics indicated hair a significant reduction in IgE and that a quantitative drop in symptoms was demonstrated. In 1992, Belen Anibarro, extensions MD, studied five children with asthma with metabisulfite intolerance confirmed by oral challenge testing. The test was repeated after premedication with 1.5 mg of oral cyanocobalamin. In four of the five patients treated, bronchospasm did not develop funky in the second metabisulfite challenge. hair and extensions.